Publications: complete list
Showing results 1 - 10 out of 959
2025
Akula, R. K., El Kilani, H., Metzen, A., Röske, J., Zhang, K., Göhl, M., Arisetti, N., Marsh, G. P., Maple, H. J., Cooper, M. S., Karadogan, B., Jochmans, D., Neyts, J., Rox, K., Hilgenfeld, R., & Brönstrup, M. (2025). Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease. Journal of medicinal chemistry, 68(3), 2920–2941. https://doi.org/10.1021/acs.jmedchem.4c02172
Brvar, M., O’Neill, T. J., Plettenburg, O., & Krappmann, D. (2025). An updated patent review of MALT1 inhibitors (2021–present). Expert Opinion on Therapeutic Patents. Advance online publication. https://doi.org/10.1080/13543776.2025.2484371
Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., & Kirschning, A. (2025). Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus. Nature Communications, 16(1), Article 2464. https://doi.org/10.1038/s41467-025-57013-3
Guo, Y., Navarro-Muñoz, J., Rodenbach, C., Dwars, E., Dieleman, C., van den Hout, B., Sanders, B., Zhou, M., Arogunjo, A., Cox, R. J., Driessen, A. J. M., & Collemare, J. (2025). Identification of a Biosynthetic Gene Cluster for the Production of the Blue-Green Pigment Xylindein by the Fungus Chlorociboria aeruginascens. Journal of natural products, 88(2), 233-244. https://doi.org/10.1021/acs.jnatprod.4c00350
Hakim, S. E., Liu, S., Herzog, R., Arafa, A., de Vries, J., Dräger, G., & Franke, J. (2025). Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants. Journal of the American Chemical Society, 147(12), 10320-10330. https://doi.org/10.1021/jacs.4c16956
Mozūraitis, R., Cirksena, K., Raftari, M., Hajkazemian, M., Mustapha Abiodun, M., Brahimi, J., Radžiutė, S., Apšegaitė, V., Bernotienė, R., Ignatowicz, L., Hick, T., Kirschning, A., Lenman, A., Gerold, G., & Emami, S. N. (Accepted/in press). Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting. Communications Biology, 8(1), 139. Article 139. https://doi.org/10.1038/s42003-025-07543-9
Ravkina, V., Dräger, G., Droste, J., Schwörer, S., Hassanin, A., Davari, M. D., & Kirschning, A. (2025). Expanding the “Terpenome”: Diterpene Synthases Accept GGPP-Ether Substrates. ACS catalysis, 6796-6811. Advance online publication. https://doi.org/10.1021/acscatal.5c00272
Schmidt, K., Charria-Girón, E., Gorelik, T. E., Kleeberg, C., Muema, J. M., Heitkämper, S., Verwaaijen, B., Kuhnert, E., Gerke, J., Kalinowski, J., Hyde, K. D., Stadler, M., Cox, R., & Surup, F. (2025). Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense. CHEMBIOCHEM. Advance online publication. https://doi.org/10.1002/cbic.202500037
Struwe, H., Nguyen, T., Schwörer, S., Droste, J., Spinck, H., & Kirschning, A. (2025). Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives. Biochemistry, 64(2), 498–508. https://doi.org/10.1021/acs.biochem.4c00589
Struwe, H., Grimm, C., Dräger, G., Beutel, S., Alcalde, M., Kirschning, A., & Kara, S. (2025). Expanding the “Terpenome”: Applications of Unspecific Peroxygenases (UPOs) in Oxidations of Unnatural Terpenoids. CHEMCATCHEM, 17(1), Article e202401414. https://doi.org/10.1002/cctc.202401414
