List of Publications Prof. Dr. Andreas Kirschning
Showing results 1 - 10 out of 333
2025
Ravkina, V., Dräger, G., Droste, J., Schwörer, S., Hassanin, A., Davari, M. D., & Kirschning, A. (2025). Expanding the “Terpenome”: Diterpene Synthases Accept GGPP-Ether Substrates. ACS catalysis, 6796-6811. Advance online publication. https://doi.org/10.1021/acscatal.5c00272
Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., & Kirschning, A. (2025). Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus. Nature Communications, 16(1), Article 2464. https://doi.org/10.1038/s41467-025-57013-3
Mozūraitis, R., Cirksena, K., Raftari, M., Hajkazemian, M., Mustapha Abiodun, M., Brahimi, J., Radžiutė, S., Apšegaitė, V., Bernotienė, R., Ignatowicz, L., Hick, T., Kirschning, A., Lenman, A., Gerold, G., & Emami, S. N. (Accepted/in press). Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting. Communications Biology, 8(1), 139. Article 139. https://doi.org/10.1038/s42003-025-07543-9
Struwe, H., Grimm, C., Dräger, G., Beutel, S., Alcalde, M., Kirschning, A., & Kara, S. (2025). Expanding the “Terpenome”: Applications of Unspecific Peroxygenases (UPOs) in Oxidations of Unnatural Terpenoids. CHEMCATCHEM, 17(1), Article e202401414. https://doi.org/10.1002/cctc.202401414
Struwe, H., Nguyen, T., Schwörer, S., Droste, J., Spinck, H., & Kirschning, A. (2025). Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives. Biochemistry, 64(2), 498–508. https://doi.org/10.1021/acs.biochem.4c00589
2024
Fricke, F., Dräger, G., & Kirschning, A. (2024). The “factory in a lab”: telescoping the Matteson and Matteson-Hoppe-Aggarwal boronate chemistry under flow conditions. Reaction Chemistry and Engineering. Advance online publication. https://doi.org/10.1039/d4re00394b
Stappert, M., Kohnhäuser, D., Seedorf, T., Coetzee, J., Rox, K., Fuchs, H. L. S., Cirnski, K., Leitner, C., Herrmann, J., Kirschning, A., Müller, R., & Brönstrup, M. (2024). Synthetic studies on the tetrasubstituted D-ring of cystobactamids lead to potent terephthalic acid antibiotics. Communications Chemistry, 7(1), Article 252. https://doi.org/10.1038/s42004-024-01337-6
Kohnhäuser, D., Seedorf, T., Cirnski, K., Heimann, D., Coetzee, J., Sordello, S., Richter, J., Stappert, M., Sabuco, J. F., Corbett, D., Bacque, E., Rox, K., Herrmann, J., Vassort, A., Muller, R., Kirschning, A., & Bronstrup, M. (2024). Optimization of the Central α-Amino Acid in Cystobactamids to the Broad-Spectrum, Resistance-Breaking Antibiotic CN-CC-861. Journal of medicinal chemistry, 67(19), 17162-17190. https://doi.org/10.1021/acs.jmedchem.4c00927
Struwe, H., Li, H., Schrödter, F., Höft, L., Fohrer, J., Dickschat, J. S., & Kirschning, A. (2024). Telescoping a Prenyltransferase and a Diterpene Synthase to Transform Unnatural FPP Derivatives to Diterpenoids. Organic letters, 26(28), 5888-5892. https://doi.org/10.1021/acs.orglett.4c01670
Moeller, M., Dhar, D., Dräger, G., Özbasi, M., Struwe, H., Wildhagen, M., Davari, M. D., Beutel, S., & Kirschning, A. (2024). Sesquiterpene Cyclase BcBOT2 Promotes the Unprecedented Wagner-Meerwein Rearrangement of the Methoxy Group. Journal of the American Chemical Society, 146(26), 17838-17846. https://doi.org/10.1021/jacs.4c03386
