Publications of the Natural Product Synthesis Group

2012


Aurich, A., Specht, R., Müller, R. A., Stottmeister, U., Yovkova, V., Otto, C., Holz, M., Barth, G., Heretsch, P., Thomas, F. A., Sicker, D., & Giannis, A. (2012). Microbiologically produced carboxylic acids used as building blocks in organic synthesis. Subcellular Biochemistry, 64, 391-423. https://doi.org/10.1007/978-94-007-5055-5_19

2011


Nicolaou, K. C., Simmons, N. L., Ying, Y., Heretsch, P. M., & Chen, J. S. (2011). Enantioselective Dichlorination of Allylic Alcohols. Journal of the American Chemical Society, 133(21), 8134-8137. https://doi.org/10.1021/ja202555m
Heretsch, P., Buettner, A., Tzagkaroulaki, L., Zahn, S., Kirchner, B., & Giannis, A. (2011). Exo-Cyclopamine-a stable and potent inhibitor of hedgehog-signaling. Chemical communications, 47(26), 7362-7364. https://doi.org/10.1039/c1cc11782c

2010


Heretsch, P., Tzagkaroulaki, L., & Giannis, A. (2010). Modulators of the hedgehog signaling pathway. Bioorganic and Medicinal Chemistry, 18(18), 6613-6624. https://doi.org/10.1016/j.bmc.2010.07.038
Heretsch, P., Rabe, S., & Giannis, A. (2010). A Biomimetic Approach to C-nor-D-homo-Steroids. Journal of the American Chemical Society, 132(29), 9968-9969. https://doi.org/10.1021/ja103152k
Heretsch, P., Tzagkaroulaki, L., & Giannis, A. (2010). Cyclopamine and Hedgehog Signaling: Chemistry, Biology, Medical Perspectives. Angewandte Chemie - International Edition, 49(20), 3418-3427. https://doi.org/10.1002/anie.200906967

2009


Heretsch, P., Rabe, S., & Giannis, A. (2009). Synthesis of All Diastereomers of the Piperidine-Alkaloid Substructure of Cyclopamine. Organic letters, 11(23), 5410-5412. https://doi.org/10.1021/ol902270f
Giannis, A., Heretsch, P., Sarli, V., & Stossel, A. (2009). Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach. Angewandte Chemie - International Edition, 48(42), 7911-7914. https://doi.org/10.1002/anie.200902520

2008


Heretsch, P., Thomas, F., Aurich, A., Krautscheid, H., Sicker, D., & Giannis, A. (2008). Syntheses with a chiral building block from the citric acid cycle: (2R,3S)-Isocitric acid by fermentation of sunflower oil. Angewandte Chemie - International Edition, 47(10), 1958-1960. https://doi.org/10.1002/anie.200705000

2007


Heretsch, P., & Giannis, A. (2007). An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues. SYNTHESIS-STUTTGART, (17), 2614-2616. https://doi.org/10.1055/s-2007-983843