Research Groups
Franke Group

Research group Dr. Franke

Plant Natural Products

We study how plants make complex natural products with medicinal properties. For this, we use a combination of chemical, molecular biological, biochemical, plant biological and bioinformatics methods. Our aim is to understand the molecular mechanisms underlying plant biosynthetic pathways and translate this knowledge into better exploitation of valuable plant compounds.

Plant Natural Products

We study how plants make complex natural products with medicinal properties. For this, we use a combination of chemical, molecular biological, biochemical, plant biological and bioinformatics methods. Our aim is to understand the molecular mechanisms underlying plant biosynthetic pathways and translate this knowledge into better exploitation of valuable plant compounds.

RESEARCH TOPICS

Two centrals questions drive our research:

  1. Pathway Elucidation: How do plants make complex natural products? Which genes and enzymes are required? What are the chemical mechanisms involved? How is the formation orchestrated across multiple types of cells and tissues?
  2. Metabolic Engineering: How can we manipulate plant biosynthetic pathways in a targeted manner? How can we generate larger quantities of rare natural products? How can the product profile be changed? Can we generate analogues of natural products in biological systems, which are otherwise only accessible by total synthesis?
Interested in joining our team?

We are looking for motivated students interested in doing a Bachelor/Master thesis or a practical course at the interface between natural product chemistry, biochemistry, molecular biology and plant sciences. If you are interested please send an e-mail to Jakob Franke.


At the moment, we have no funded PhD and postdoc positions available. If you have external funding or want to apply for external funding, please feel encouraged to contact Jakob Franke with a CV.