List of Publications Prof. Dr. Andreas Kirschning
2026
Taser, D., Victoria, C., Garrel, L. V., Droste, J., Tabet, C., Dräger, G., Hassanin, A., Davari, M. D., & Kirschning, A. (2026). Introducing Small Rings into Farnesyl Pyrophosphates Paves the Way for the Enzymatic Generation of Unnatural Sesquiterpene Scaffolds. Journal of the American Chemical Society, 148(5), 5496-5507. https://doi.org/10.1021/jacs.5c19651
Struwe, H., Slotman, C., Höft, L., Dräger, G., Droste, J., Fohrer, J., Hausmann, K., Beutel, S., Kolling, D., Köhnke, J., & Kirschning, A. (2026). Chemoenzymatic Synthesis of Structurally Diverse Terpenoids from Farnesyl Pyrophosphates Modified at the Central Alkene Unit. Journal of the American Chemical Society, 148(1), 525-536. https://doi.org/10.1021/jacs.5c14636
Neubeck, A., & Kirschning, A. (2026). Nickel: Geochemistry, biochemistry and its role in chemical and biological evolutions. Earth-Science Reviews, 272, Article 105324. https://doi.org/10.1016/j.earscirev.2025.105324
2025
Yadav, K., Kalita, T., Sharma, L., Pandit, A., Pathak, B., Dräger, G., Kirschning, A., & Chelvam, V. (2025). Design, Synthesis, and Cytotoxic Evaluation of New Structurally Simplified and Highly Potent Third-Generation Tubulysin Derivatives. Chemistry - a European journal, 31(46), Article e01965. https://doi.org/10.1002/chem.202501965
Jäger, B., Budde, J. L., Birke, N., Hauke, M., & Kirschning, A. (2025). Chemoenzymatic Generation of Thio-analogues of δ-Cadinene, δ-Cadinol, and a Thio-diquinane Using 8-Thio-farnesylpyrophosphate. Journal of natural products, 88(7), 1653-1662. https://doi.org/10.1021/acs.jnatprod.5c00409
Budde, J. L., Çay, M. Y., Dräger, G., Droste, J., Hassanin, A., Davari, M. D., & Kirschning, A. (2025). Reprogramming the Cyclization of the Sesquiterpene Synthase BcBOT2 Using 2,3-Z-Configured FPP Derivatives and by Means of “Methyl Mapping”. ACS catalysis, 15(10), 8125-8139. https://doi.org/10.1021/acscatal.5c01224
Ravkina, V., Dräger, G., Droste, J., Schwörer, S., Hassanin, A., Davari, M. D., & Kirschning, A. (2025). Expanding the “Terpenome”: Diterpene Synthases Accept GGPP-Ether Substrates. ACS catalysis, 15(9), 6796-6811. https://doi.org/10.1021/acscatal.5c00272
Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., & Kirschning, A. (2025). Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus. Nature Communications, 16(1), Article 2464. https://doi.org/10.1038/s41467-025-57013-3
Mozūraitis, R., Cirksena, K., Raftari, M., Hajkazemian, M., Mustapha Abiodun, M., Brahimi, J., Radžiutė, S., Apšegaitė, V., Bernotienė, R., Ignatowicz, L., Hick, T., Kirschning, A., Lenman, A., Gerold, G., & Emami, S. N. (2025). Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting. Communications Biology, 8(1), Article 139. https://doi.org/10.1038/s42003-025-07543-9
Struwe, H., Grimm, C., Dräger, G., Beutel, S., Alcalde, M., Kirschning, A., & Kara, S. (2025). Expanding the “Terpenome”: Applications of Unspecific Peroxygenases (UPOs) in Oxidations of Unnatural Terpenoids. CHEMCATCHEM, 17(1), Article e202401414. https://doi.org/10.1002/cctc.202401414