Publikationen der Arbeitsgruppe Synthetische Biologie

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Gao, S. S., Wang, L., Song, Z., Hothersall, J., Stevens, E. R., Connolly, J., Winn, P. J., Cox, R. J., Crump, M. P., Race, P. R., Thomas, C. M., Simpson, T. J., & Willis, C. L. (2017). Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics. Angewandte Chemie , 56(14), 3930-3934.,
Feng, J., Zhang, P., Cui, Y., Li, K., Qiao, X., Zhang, Y. T., Li, S. M., Cox, R. J., Wu, B., Ye, M., & Yin, W. B. (2017). Regio- and Stereospecific O-Glycosylation of Phenolic Compounds Catalyzed by a Fungal Glycosyltransferase from Mucor hiemalis. Advanced Synthesis and Catalysis, 359(6), 995-1006.,
Williams, K., Szwalbe, A. J., Dickson, C., Desson, T. R., Mulholland, N. P., Vincent, J. L., Clough, J. M., Bailey, A. M., Butts, C. P., Willis, C. L., Simpson, T. J., & Cox, R. J. (2017). Genetic and chemical characterisation of the cornexistin pathway provides further insight into maleidride biosynthesis. Chemical communications, 53(56), 7965-7968.
Liddle, E., Scott, A., Han, L. C., Ivison, D., Simpson, T. J., Willis, C. L., & Cox, R. J. (2017). In vitro kinetic study of the squalestatin tetraketide synthase dehydratase reveals the stereochemical course of a fungal highly reducing polyketide synthase. Chemical communications, 53(10), 1727-1730.
Chen, W., Chen, R., Liu, Q., He, Y., He, K., Ding, X., Kang, L., Guo, X., Xie, N., Zhou, Y., Lu, Y., Cox, R. J., Molnár, I., Li, M., Shao, Y., & Chen, F. (2017). Orange, red, yellow: Biosynthesis of azaphilone pigments in Monascus fungi. Chemical science, 8(7), 4917-4925.
Roberts, D. M., Bartel, C., Scott, A., Ivison, D., Simpson, T. J., & Cox, R. J. (2017). Substrate selectivity of an isolated enoyl reductase catalytic domain from an iterative highly reducing fungal polyketide synthase reveals key components of programming. Chemical science, 8(2), 1116-1126.


Khan, A. A., Bacha, N., Ahmad, B., Cox, R. J., & Bakht, J. (2016). Role of growth media and chemical enhancers in secondary metabolites production from Aspergillus carbonarius (NRL-369) and their pharmaceutical potentials. Pakistan Journal of Pharmaceutical Sciences, 29(4), 1223-1230.
Griffiths, S., Mesarich, C. H., Saccomanno, B., Vaisberg, A., De Wit, P. J. G. M., Cox, R., & Collemare, J. (2016). Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization. Proceedings of the National Academy of Sciences of the United States of America, 113(25), 6851-6856.
Williams, K., Szwalbe, A. J., Mulholland, N. P., Vincent, J. L., Bailey, A. M., Willis, C. L., Simpson, T. J., & Cox, R. J. (2016). Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis. Angewandte Chemie , 55(23), 6784-6788.,
Bailey, A. M., Alberti, F., Kilaru, S., Collins, C. M., De Mattos-Shipley, K., Hartley, A. J., Hayes, P., Griffin, A., Lazarus, C. M., Cox, R. J., Willis, C. L., O'Dwyer, K., Spence, D. W., & Foster, G. D. (2016). Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production. Scientific reports, 6, Artikel 25202.