Publikationen der Arbeitsgruppe Synthetische Biologie

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2010


Skellam, E. J., Hurley, D., Davison, J., Lazarus, C. M., Simpson, T. J., & Cox, R. J. (2010). Mutation of key residues in the C-methyltransferase domain of a fungal highly reducing polyketide synthase. Molecular BioSystems, 6(4), 680-682. https://doi.org/10.1039/b923990a
Wattana-amorn, P., Williams, C., Ploskoń, E., Cox, R. J., Simpson, T. J., Crosby, J., & Crump, M. P. (2010). Solution structure of an acyl carrier protein domain from a fungal type i polyketide synthase. Biochemistry, 49(10), 2186-2193. https://doi.org/10.1021/bi902176v
Cox, R. J., & Simpson, T. J. (2010). Fungal type I polyketides. In Comprehensive Natural Products II: Chemistry and Biology (Band 1, S. 347-383). Elsevier Ltd..
Fisch, K. M., Skellam, E., Ivison, D., Cox, R. J., Bailey, A. M., Lazarus, C. M., & Simpson, T. J. (2010). Catalytic role of the C-terminal domains of a fungal non-reducing polyketide synthase. Chemical communications, 46(29), 5331-5333. https://doi.org/10.1039/c0cc01162b
Cox, R. J., Halo, L. M., & Heneghan, M. N. (2010). Expression of complete fungal biosynthetic gene clusters by promoter replacement in Aspergillus oryzae. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
Wu, J., Zhang, H. B., Xu, J. L., Cox, R. J., Simpson, T. J., & Zhang, L. H. (2010). 13C Labeling reveals multiple amination reactions in the biosynthesis of a novel polyketide polyamine antibiotic zeamine from Dickeya zeae. Chemical communications, 46(2), 333-335. https://doi.org/10.1039/b916307g

2009


Evans, S. E., Williams, C., Arthur, C. J., Płoskoń, E., Wattana-amorn, P., Cox, R. J., Crosby, J., Willis, C. L., Simpson, T. J., & Crump, M. P. (2009). Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). Journal of molecular biology, 389(3), 511-528. https://doi.org/10.1016/j.jmb.2009.03.072
Beltran-Alvarez, P., Arthur, C. J., Cox, R. J., Crosby, J., Crump, M. P., & Simpson, T. J. (2009). Preliminary kinetic analysis of acyl carrier protein-ketoacylsynthase interactions in the actinorhodin minimal polyketide synthase. Molecular BioSystems, 5(5), 511-518. https://doi.org/10.1039/b821844g
Cox, R. J., & Simpson, T. J. (2009). Chapter 3 Fungal Type I Polyketide Synthases. In D. Hopwood (Hrsg.), Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates (B Aufl., S. 49-78). (Methods in Enzymology; Band 459, Nr. B). https://doi.org/10.1016/S0076-6879(09)04603-5

2008


Halo, L. M., Heneghan, M. N., Yakasai, A. A., Song, Z., Williams, K., Bailey, A. M., Cox, R. J., Lazarus, C. M., & Simpson, T. J. (2008). Late stage oxidations during the biosynthesis of the 2-pyridone tenellin in the entomopathogenic fungus beauveria bassiana. Journal of the American Chemical Society, 130(52), 17988-17996. https://doi.org/10.1021/ja807052c

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