Zeige Ergebnisse 31 - 40 von 47
2014
Nicolaou, K. C., Heretsch, P., ElMarrouni, A., Hale, C. R. H., Pulukuri, K. K., Kudva, A. K., Narayan, V., & Prabhu, K. S. (2014). Total Synthesis of Delta(12)-Prostaglandin J(3), a Highly Potent and Selective Antileukemic Agent. Angewandte Chemie - International Edition, 53(39), 10443-10447. https://doi.org/10.1002/anie.201404917
Rabe, S., Moschner, J., Bantzi, M., Heretsch, P., & Giannis, A. (2014). C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog. Beilstein Journal of Organic Chemistry, 10, 1564-1568. https://doi.org/10.3762/bjoc.10.161
Heretsch, P., & Giannis, A. (2014). Cyclopamine and Congeners. In Natural Products in Medicinal Chemistry (S. 545-564). Wiley-Blackwell. https://doi.org/10.1002/9783527676545.ch15
2013
Moschner, J., Chentsova, A., Eilert, N., Rovardi, I., Heretsch, P., & Giannis, A. (2013). Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling. Beilstein Journal of Organic Chemistry, 9, 2328-2335. https://doi.org/10.3762/bjoc.9.267
Mishra, O. P., Simmons, N., Tyagi, S., Pietrofesa, R., Shuvaev, V. V., Valiulin, R. A., Heretsch, P., Nicolaou, K. C., & Christofidou-Solomidou, M. (2013). Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorganic and Medicinal Chemistry Letters, 23(19), 5325-5328. https://doi.org/10.1016/j.bmcl.2013.07.062
Nicolaou, K. C., Yu, R., Shi, L., Cai, Q., Lu, M., & Heretsch, P. (2013). General Synthetic Approach to Functionalized Dihydrooxepines. Organic letters, 15(8), 1994-1997. https://doi.org/10.1021/ol4006689
2012
Nicolaou, K. C., Lu, M., Totokotsopoulos, S., Heretsch, P., Giguere, D., Sun, Y-P., Sarlah, D., Nguyen, T. H., Wolf, I. C., Smee, D. F., Day, C. W., Bopp, S., & Winzeler, E. A. (2012). Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents. Journal of the American Chemical Society, 134(41), 17320-17332. https://doi.org/10.1021/ja308429f
Aurich, A., Specht, R., Müller, R. A., Stottmeister, U., Yovkova, V., Otto, C., Holz, M., Barth, G., Heretsch, P., Thomas, F. A., Sicker, D., & Giannis, A. (2012). Microbiologically produced carboxylic acids used as building blocks in organic synthesis. Subcellular Biochemistry, 64, 391-423. https://doi.org/10.1007/978-94-007-5055-5_19
2011
Nicolaou, K. C., Simmons, N. L., Ying, Y., Heretsch, P. M., & Chen, J. S. (2011). Enantioselective Dichlorination of Allylic Alcohols. Journal of the American Chemical Society, 133(21), 8134-8137. https://doi.org/10.1021/ja202555m
Heretsch, P., Buettner, A., Tzagkaroulaki, L., Zahn, S., Kirchner, B., & Giannis, A. (2011). Exo-Cyclopamine-a stable and potent inhibitor of hedgehog-signaling. Chemical communications, 47(26), 7362-7364. https://doi.org/10.1039/c1cc11782c
