Marchanka A, Stanek J,  Pintacuda G  and  Carlomagno T 

Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS

Chem Comm 2018 June 28, (Ahead of print) doi: link

Marchanka A, Kreutz C, Carlomagno T

Isotope labeling for studying RNA by solid-state NMR spectroscopy.

J Biomol NMR. 2018 Apr 12. (Ahead of print) doi: link


Lercher L, Danilenko N, Kirkpatrick J, Carlomagno T

Structural characterization of the Asf1-Rtt109 interaction and its role in histone acetylation.

Nucleic Acids Res. 2018 Mar 16;46(5):2279-2289. doi: link

Karaca E, Rodrigues JPGLM, Graziadei A, Bonvin AMJJ, Carlomagno T

M3: an integrative framework for structure determination of molecular machines.

Nat Methods. 2017 Sep;14(9):897-902. doi: link

Codutti L, Grimaldi M, Carlomagno T

Structure-Based Design of Scaffolds Targeting PDE10A by INPHARMA-NMR.

J Chem Inf Model. 2017 Jun 26;57(6):1488-1498. doi: link


Miller TC, Simon B, Rybin V, Grotsch H, Curtet S, Khochbin S, Carlomagno T, Muller CW

A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT.

Nat Commun. 2016 Dec 19;7:13855. doi: link

Scherer S, Wollrab E, Codutti L, Carlomagno T, da Costa SG, Volkmer A, Bronja A, Schmitz OJ, Ott A

Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth : Part II: Gas, Oil, Water and the Oil/Water-Interface.

Orig Life Evol Biosph. 2016 Jun;47(4):381–403. doi: link

Kuhne C, Singer HM, Grabisch E, Codutti L, Carlomagno T, Scrima A, Erhardt M

RflM mediates target specificity of the RcsCDB phosphorelay system for transcriptional repression of flagellar synthesis in Salmonella enterica.

Mol Microbiol. 2016 Sep;101(5):841-55. doi: link

Kozak S, Lercher L, Karanth MN, Meijers R, Carlomagno T, Boivin S

Optimization of protein samples for NMR using thermal shift assays.

J Biomol NMR. 2016 Apr;64(4):281-9. doi: link

Graziadei A, Masiewicz P, Lapinaite A, Carlomagno T

Archaea box C/D enzymes methylate two distinct substrate rRNA sequences with different efficiency.

RNA. 2016 May;22(5):764-72. doi: link

Bowman A, Lercher L, Singh HR, Zinne D, Timinszky G, Carlomagno T, Ladurner AG

The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats.

Nucleic Acids Res. 2016 Apr 20;44(7):3105-17. doi: link

Wollrab E, Scherer S, Aubriet F, Carre V, Carlomagno T, Codutti L, Ott A

Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth: Part I: Chemical Diversity, Oxygen and Nitrogen Based Polymers.

Orig Life Evol Biosph. 2016 Jun;46(2-3):149-69. doi: link


Onila I, ten Brink T, Fredriksson K, Codutti L, Mazur A, Griesinger C, Carlomagno T, Exner TE

On-the-Fly Integration of Data from a Spin-Diffusion-Based NMR Experiment into Protein-Ligand Docking.

J Chem Inf Model. 2015 Sep 28;55(9):1962-72. doi: link

Codutti L, Leppek K, Zalesak J, Windeisen V, Masiewicz P, Stoecklin G, Carlomagno T

A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.

Structure. 2015 Aug 4;23(8):1437-47. doi: link

Simon B, Masiewicz P, Ephrussi A, Carlomagno T

The structure of the SOLE element of oskar mRNA.

RNA. 2015 Aug;21(8):1444-53. doi: link

J. Sikorska, L. Codutti, L. Skjærven, B. Elshorst, R. Saez-Ameneiro, A. Angelini, P. Monecke, T. Carlomagno

Identification of new scaffolds with INPHARMA-based virtual screening.

Med Chem Com 2015(6):1501-07. doi: link

DOI: no DOI available

Marchanka A, Simon B, Althoff-Ospelt G, Carlomagno T

RNA structure determination by solid-state NMR spectroscopy.

Nat Commun. 2015 May 11;6:7024. doi: link


A. Marchanka T. Carlomagno

Solid-state NMR and RNA Structure: A new Partnership?

eMagRes 2014 3, 119–128. doi: link

Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, Müller CW, van Noort V, Beck M, Bork P. (2014)

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.

Nucleic Acids Res. 42(22):13525-13533. doi:10.1093/nar/gku1147
Europe PMC | doi

Findeisen P, Mühlhausen S, Dempewolf S, Hertzog J, Zietlow A, Carlomagno T, Kollmar M. (2014)

Six subgroups and extensive recent duplications characterize the evolution of the eukaryotic tubulin protein family

Genome Biol Evol 6(9):2274-2288. doi:10.1093/gbe/evu187
Europe PMC | doi

Carlomagno T. (2014)

Present and future of NMR for RNA-protein complexes: a perspective of integrated structural biology

J. Magn. Reson. 241:126-136. doi:10.1016/j.jmr.2013.10.007
Europe PMC | doi

Canales A, Nieto L, Rodríguez-Salarichs J, Sánchez-Murcia PA, Coderch C, Cortés-Cabrera A, Paterson I, Carlomagno T, Gago F, Andreu JM, Altmann KH, Jiménez-Barbero J, Díaz JF. (2014)

Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.

ACS Chem. Biol. 9(4):1033-1043. doi:10.1021/cb400673h
Europe PMC | doi




Lapinaite A, Simon B, Skjaerven L, Rakwalska-Bange M, Gabel F, Carlomagno T. (2013)

The structure of the box C/D enzyme reveals regulation of RNA methylation

Nature 502(7472):519-523. doi:10.1038/nature12581
Europe PMC | doi

Schulte B, John I, Simon B, Brockmann C, Oelmeier SA, Jahraus B, Kirchgessner H, Riplinger S, Carlomagno T, Wabnitz GH, Samstag Y. (2013)

A reducing milieu renders cofilin insensitive to phosphatidylinositol 4,5-bisphosphate (PIP2) inhibition

J. Biol. Chem. 288(41):29430-29439. doi:10.1074/jbc.m113.479766
Europe PMC | doi

Marchanka A, Simon B, Carlomagno T. (2013)

A suite of solid-state NMR experiments for RNA intranucleotide resonance assignment in a 21 kDa protein-RNA complex

Angew. Chem. Int. Ed. Engl. 52(38):9996-10001. doi:10.1002/anie.201304779
Europe PMC | doi

Skjærven L, Codutti L, Angelini A, Grimaldi M, Latek D, Monecke P, Dreyer MK, Carlomagno T. (2013)

Accounting for conformational variability in protein-ligand docking with NMR-guided rescoring

J. Am. Chem. Soc. 135(15):5819-5827. doi:10.1021/ja4007468
Europe PMC | doi

Carlomagno T, Amata I, Codutti L, Falb M, Fohrer J, Masiewicz P, Simon B. (2013)

Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme

J. Am. Chem. Soc. 135(11):4403-4411. doi:10.1021/ja311868t
Europe PMC | doi

Asami S, Rakwalska-Bange M, Carlomagno T, Reif B. (2013)

Protein-RNA interfaces probed by 1H-detected MAS solid-state NMR spectroscopy

Angew. Chem. Int. Ed. Engl. 52(8):2345-2349. doi:10.1002/anie.201208024
Europe PMC | doi

Latek D, Pasznik P, Carlomagno T, Filipek S. (2013)

Towards improved quality of GPCR models by usage of multiple templates and profile-profile comparison

PLoS ONE 8(2):e56742. doi:10.1371/journal.pone.0056742
Europe PMC | doi




Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA, Di Croce L. (2012)

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

Nat. Struct. Mol. Biol. 19(12):1257-1265. doi:10.1038/nsmb.2434
Europe PMC | doi

Persch E, Basile T, Bockelmann S, Huss M, Wieczorek H, Carlomagno T, Menche D. (2012)


Synthesis and biological evaluation of a water-soluble derivative of the potent V-ATPase inhibitor archazolid

Bioorg. Med. Chem. Lett. 22(24):7735-7738. doi:10.1016/j.bmcl.2012.09.081
Europe PMC | doi

Stauch B, Orts J, Carlomagno T. (2012)


The description of protein internal motions aids selection of ligand binding poses by the INPHARMA method

J. Biomol. NMR 54(3):245-256. doi:10.1007/s10858-012-9662-1
Europe PMC | doi

Dreisigacker S, Latek D, Bockelmann S, Huss M, Wieczorek H, Filipek S, Gohlke H, Menche D, Carlomagno T. (2012)


Understanding the inhibitory effect of highly potent and selective archazolides binding to the vacuolar ATPase

J Chem Inf Model 52(8):2265-2272. doi:10.1021/ci300242d
Europe PMC | doi

Carlomagno T. (2012)


NMR in natural products: understanding conformation, configuration and receptor interactions

Nat Prod Rep 29(5):536-554. doi:10.1039/c2np00098a
Europe PMC | doi

Lee Y, Zeng H, Mazur A, Wegstroth M, Carlomagno T, Reese M, Lee D, Becker S, Griesinger C, Hilty C. (2012)


Hyperpolarized binding pocket nuclear Overhauser effect for determination of competitive ligand binding

Angew. Chem. Int. Ed. Engl. 51(21):5179-5182. doi:10.1002/anie.201201003
Europe PMC | doi

Orts J, Bartoschek S, Griesinger C, Monecke P, Carlomagno T. (2012)


An NMR-based scoring function improves the accuracy of binding pose predictions by docking by two orders of magnitude

J. Biomol. NMR 52(1):23-30. doi:10.1007/s10858-011-9590-5
Europe PMC | doi




Corradi V, Mancini M, Santucci MA, Carlomagno T, Sanfelice D, Mori M, Vignaroli G, Falchi F, Manetti F, Radi M, Botta M. (2011)

Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case

Bioorg. Med. Chem. Lett. 21(22):6867-6871. doi:10.1016/j.bmcl.2011.09.011
Europe PMC | doi

Simon B, Kirkpatrick JP, Eckhardt S, Reuter M, Rocha EA, Andrade-Navarro MA, Sehr P, Pillai RS, Carlomagno T. (2011)

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein

Structure 19(2):172-180. doi:10.1016/j.str.2010.11.015
Europe PMC | doi




Dervillez X, Klaukien V, Dürr R, Koch J, Kreutz A, Haarmann T, Stoll M, Lee D, Carlomagno T, Schnierle B, Möbius K, Königs C, Griesinger C, Dietrich U. (2010)

Peptide ligands selected with CD4-induced epitopes on native dualtropic HIV-1 envelope proteins mimic extracellular coreceptor domains and bind to HIV-1 gp120 independently of coreceptor usage

J. Virol. 84(19):10131-10138. doi:10.1128/jvi.00165-10
Europe PMC | doi

Falb M, Amata I, Gabel F, Simon B, Carlomagno T. (2010)


Structure of the K-turn U4 RNA: a combined NMR and SANS study

Nucleic Acids Res. 38(18):6274-6285. doi:10.1093/nar/gkq380
Europe PMC | doi

Kumar A, Heise H, Blommers MJ, Krastel P, Schmitt E, Petersen F, Jeganathan S, Mandelkow EM, Carlomagno T, Griesinger C, Baldus M. (2010)

Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy

Angew. Chem. Int. Ed. Engl. 49(41):7504-7507. doi:10.1002/anie.201001946
Europe PMC | doi

Bülow L, Nickeleit I, Girbig AK, Brodmann T, Rentsch A, Eggert U, Sasse F, Steinmetz H, Frank R, Carlomagno T, Malek NP, Kalesse M. (2010)

Synthesis and biological characterization of argyrin F

ChemMedChem 5(6):832-836. doi:10.1002/cmdc.201090023
Europe PMC | doi

Erdélyi M, Navarro-Vázquez A, Pfeiffer B, Kuzniewski CN, Felser A, Widmer T, Gertsch J, Pera B, Díaz JF, Altmann KH, Carlomagno T. (2010)

The binding mode of side chain- and C3-modified epothilones to tubulin

ChemMedChem 5(6):911-920. doi:10.1002/cmdc.201000050
Europe PMC | doi

Kubicek K, Grimm SK, Orts J, Sasse F, Carlomagno T. (2010)

The tubulin-bound structure of the antimitotic drug tubulysin

Angew. Chem. Int. Ed. Engl. 49(28):4809-4812. doi:10.1002/anie.200906828
Europe PMC | doi

Stauch B, Simon B, Basile T, Schneider G, Malek NP, Kalesse M, Carlomagno T. (2010)

Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling

Angew. Chem. Int. Ed. Engl. 49(23):3934-3938. doi:10.1002/anie.201000140
Europe PMC | doi

Rodríguez-Castañeda F, Coudevylle N, Becker S, Brose N, Carlomagno T, Griesinger C. (2010)

1H, 13C and 15N resonance assignments of the Calmodulin-Munc13-1 peptide complex

Biomol NMR Assign 4(1):45-48. doi:10.1007/s12104-009-9204-2
Europe PMC | doi

Jehle S, Falb M, Kirkpatrick JP, Oschkinat H, van Rossum BJ, Althoff G, Carlomagno T. (2010)

Intermolecular protein-RNA interactions revealed by 2D 31P-15N magic angle spinning solid-state NMR spectroscopy

J. Am. Chem. Soc. 132(11):3842-3846. doi:10.1021/ja909723f
Europe PMC | doi

Bartoschek S, Klabunde T, Defossa E, Dietrich V, Stengelin S, Griesinger C, Carlomagno T, Focken I, Wendt KU. (2010)

Drug design for G-protein-coupled receptors by a ligand-based NMR method

Angew. Chem. Int. Ed. Engl. 49(8):1426-1429. doi:10.1002/anie.200905102
Europe PMC | doi

Rodríguez-Castañeda F, Maestre-Martínez M, Coudevylle N, Dimova K, Junge H, Lipstein N, Lee D, Becker S, Brose N, Jahn O, Carlomagno T, Griesinger C. (2010)

Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity

EMBO J. 29(3):680-691. doi:10.1038/emboj.2009.373
Europe PMC | doi




Orts J, Griesinger C, Carlomagno T. (2009)

The INPHARMA technique for pharmacophore mapping: A theoretical guide to the method

J. Magn. Reson. 200(1):64-73. doi:10.1016/j.jmr.2009.06.006
Europe PMC | doi

Li P, Kirkpatrick J, Carlomagno T. (2009)

An efficient strategy for the determination of the three-dimensional architecture of ribonucleoprotein complexes by the combination of a few easily accessible NMR and biochemical data: intermolecular recognition in a U4 spliceosomal complex

J. Mol. Biol. 388(2):283-298. doi:10.1016/j.jmb.2009.03.001
Europe PMC | doi

Kirkpatrick JP, Li P, Carlomagno T. (2009)

Probing mutation-induced structural perturbations by refinement against residual dipolar couplings: application to the U4 spliceosomal RNP complex

Chembiochem 10(6):1007-1014. doi:10.1002/cbic.200800786
Europe PMC | doi




Carlomagno T, Amata I, Williamson JR, Hennig M. (2008)

NMR assignments of HIV-2 TAR RNA

Biomol NMR Assign 2(2):167-169. doi:10.1007/s12104-008-9112-x
Europe PMC | doi

Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sörensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gütgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP. (2008)

Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition

Cancer Cell 14(1):23-35. doi:10.1016/j.ccr.2008.05.016
Europe PMC | doi

Erdélyi M, Pfeiffer B, Hauenstein K, Fohrer J, Gertsch J, Altmann KH, Carlomagno T. (2008)

Conformational preferences of natural and C3-modified epothilones in aqueous solution

J. Med. Chem. 51(5):1469-1473. doi:10.1021/jm7013452
Europe PMC | doi

Höfer P, Parigi G, Luchinat C, Carl P, Guthausen G, Reese M, Carlomagno T, Griesinger C, Bennati M. (2008)

Field dependent dynamic nuclear polarization with radicals in aqueous solution

J. Am. Chem. Soc. 130(11):3254-3255. doi:10.1021/ja0783207
Europe PMC | doi

Farès C, Hassfeld J, Menche D, Carlomagno T. (2008)

Simultaneous determination of the conformation and relative configuration of archazolide a by using nuclear overhauser effects, J couplings, and residual dipolar couplings

Angew. Chem. Int. Ed. Engl. 47(20):3722-3726. doi:10.1002/anie.200800225
Europe PMC | doi

Hofer P, Carl P, Guthausen G, Prisner T, Reese M, Carlomagno T, Griesinger C, Bennati M. (2008)

Studies of dynamic nuclear polarization with nitroxides in aqueous solution

Appl Magn Reson 34(3-4):393-398.
Europe PMC

Orts J, Grimm SK, Griesinger C, Wendt KU, Bartoschek S, Carlomagno T. (2008)

Specific methyl group protonation for the measurement of pharmacophore-specific interligand NOE interactions

Chemistry 14(25):7517-7520. doi:10.1002/chem.200800880
Europe PMC | doi

Orts J, Tuma J, Reese M, Grimm SK, Monecke P, Bartoschek S, Schiffer A, Wendt KU, Griesinger C, Carlomagno T. (2008)

Crystallography-independent determination of ligand binding modes

Angew. Chem. Int. Ed. Engl. 47(40):7736-7740. doi:10.1002/anie.200801792
Europe PMC | doi

Reese M, Lennartz D, Marquardsen T, Hofer P, Tavernier A, Carl P, Schippmann T, Bennati M, Carlomagno T, Engelke F, Griesinger C. (2008)

Construction of a liquid-state NMR DNP shuttle spectrometer: First experimental results and evaluation of optimal performance characteristics

Appl Magn Reson 34(3-4):301-311.
Europe PMC




Farès C, Amata I, Carlomagno T. (2007)

13C-detection in RNA bases: revealing structure-chemical shift relationships

J. Am. Chem. Soc. 129(51):15814-15823. doi:10.1021/ja0727417
Europe PMC | doi

Lange A, Schupp T, Petersen F, Carlomagno T, Baldus M. (2007)

High-resolution solid-state NMR structure of an anticancer agent

ChemMedChem 2(4):522-527. doi:10.1002/cmdc.200600299
Europe PMC | doi

Liu S, Li P, Dybkov O, Nottrott S, Hartmuth K, Lührmann R, Carlomagno T, Wahl MC. (2007)

Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP

Science 316(5821):115-120. doi:10.1126/science.1137924
Europe PMC | doi

Carlomagno T, Baldus M, Griesinger C. (2007)

Bio-nuclear magnetic resonance

Europe PMC | doi

Reese M, Sánchez-Pedregal VM, Kubicek K, Meiler J, Blommers MJ, Griesinger C, Carlomagno T. (2007)

Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution

Angew. Chem. Int. Ed. Engl. 46(11):1864-1868. doi:10.1002/anie.200604505
Europe PMC | doi




Sánchez-Pedregal VM, Kubicek K, Meiler J, Lyothier I, Paterson I, Carlomagno T. (2006)

The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide

Angew. Chem. Int. Ed. Engl. 45(44):7388-7394. doi:10.1002/anie.200602793
Europe PMC | doi

Fohrer J, Reinscheid U, Hennig M, Carlomagno T. (2006)

Calculation of the dependence of homo- and heteronuclear 3J and 2J scalar couplings for the determination of the 2'-hydroxy conformation in RNA

Angew. Chem. Int. Ed. Engl. 45(42):7033-7036. doi:10.1002/anie.200602583
Europe PMC | doi

Hassfeld J, Farès C, Steinmetz H, Carlomagno T, Menche D. (2006)

Stereochemical determination of Archazolid A and B, highly potent vacuolar-type ATPase inhibitors from the Myxobacterium Archangium gephyra

Org. Lett. 8(21):4751-4754. doi:10.1021/ol061831y
Europe PMC | doi

Farès C, Carlomagno T. (2006)

SHARP-TACSY: triple-band tailored correlated spectroscopy for base-to-sugar transfer in nucleic acid residues with intermediate time scale motions

J. Am. Chem. Soc. 128(30):9856-9862. doi:10.1021/ja061424h
Europe PMC | doi

Fohrer J, Hennig M, Carlomagno T. (2006)

Influence of the 2'-hydroxyl group conformation on the stability of A-form helices in RNA

J. Mol. Biol. 356(2):280-287. doi:10.1016/j.jmb.2005.11.043
Europe PMC | doi

Lakomek NA, Carlomagno T, Becker S, Griesinger C, Meiler J. (2006)

A thorough dynamic interpretation of residual dipolar couplings in ubiquitin

J. Biomol. NMR 34(2):101-115. doi:10.1007/s10858-005-5686-0
Europe PMC | doi

Carlomagno T, Griesinger C. (2006)

Transferred Cross-Correlated Relaxation: Application to Drug/Target Complexes


Raghunathan D, Sánchez-Pedregal VM, Junker J, Schwiegk C, Kalesse M, Kirschning A, Carlomagno T. (2006)

TAR-RNA recognition by a novel cyclic aminoglycoside analogue

Nucleic Acids Res. 34(12):3599-3608. doi:10.1093/nar/gkl494
Europe PMC | doi




Lakomek NA, Farès C, Becker S, Carlomagno T, Meiler J, Griesinger C. (2005)

Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin

Angew. Chem. Int. Ed. Engl. 44(47):7776-7778. doi:10.1002/anie.200502573
Europe PMC | doi

Sánchez-Pedregal VM, Reese M, Meiler J, Blommers MJ, Griesinger C, Carlomagno T. (2005)

The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping

Angew. Chem. Int. Ed. Engl. 44(27):4172-4175. doi:10.1002/anie.200500503
Europe PMC | doi

Verdier L, Al-Sabi A, Rivier JE, Olivera BM, Terlau H, Carlomagno T. (2005)

Identification of a novel pharmacophore for peptide toxins interacting with K+ channels

J. Biol. Chem. 280(22):21246-21255. doi:10.1074/jbc.m502376200
Europe PMC | doi

Hennig M, Fohrer J, Carlomagno T. (2005)

Assignment and NOE analysis of 2'-hydroxyl protons in RNA: implications for stabilization of RNA A-form duplexes

J. Am. Chem. Soc. 127(7):2028-2029. doi:10.1021/ja043390o
Europe PMC | doi

Carlomagno T. (2005)

Ligand-target interactions: what can we learn from NMR?

Annu Rev Biophys Biomol Struct 34:245-266. doi:10.1146/annurev.biophys.34.040204.144419
Europe PMC | doi




Al-Sabi A, Lennartz D, Ferber M, Gulyas J, Rivier JE, Olivera BM, Carlomagno T, Terlau H. (2004)

KappaM-conotoxin RIIIK, structural and functional novelty in a K+ channel antagonist

Biochemistry 43(27):8625-8635. doi:10.1021/bi0495681
Europe PMC | doi

Razeto A, Ramakrishnan V, Litterst CM, Giller K, Griesinger C, Carlomagno T, Lakomek N, Heimburg T, Lodrini M, Pfitzner E, Becker S. (2004)

Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain

J. Mol. Biol. 336(2):319-329. doi:10.1016/j.jmb.2003.12.057
Europe PMC | doi




Carlomagno T, Bermel W, Griesinger C. (2003)

Measuring the chi 1 torsion angle in protein by CH-CH cross-correlated relaxation: a new resolution-optimised experiment

J. Biomol. NMR 27(2):151-157. doi:10.1023/a:1024927527767
Europe PMC | doi

Kipping M, Lilie H, Lindenstrauss U, Andreesen JR, Griesinger C, Carlomagno T, Brüser T. (2003)

Structural studies on a twin-arginine signal sequence

FEBS Lett. 550(1-3):18-22. doi:10.1016/s0014-5793(03)00804-4
Europe PMC | doi

Carlomagno T, Blommers MJ, Meiler J, Jahnke W, Schupp T, Petersen F, Schinzer D, Altmann KH, Griesinger C. (2003)

The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents

Angew. Chem. Int. Ed. Engl. 42(22):2511-2515. doi:10.1002/anie.200351276
Europe PMC | doi

Carlomagno T, Sánchez VM, Blommers MJ, Griesinger C. (2003)

Derivation of dihedral angles from CH-CH dipolar-dipolar cross-correlated relaxation rates: a C-C torsion involving a quaternary carbon atom in epothilone A bound to tubulin

Angew. Chem. Int. Ed. Engl. 42(22):2515-2517. doi:10.1002/anie.200350950
Europe PMC | doi




Carlomagno T, Hennig M, Williamson JR. (2002)

A novel PH-cT-COSY methodology for measuring JPH coupling constants in unlabeled nucleic acids. application to HIV-2 TAR RNA

J. Biomol. NMR 22(1):65-81. doi:10.1023/a:1013811631477
Europe PMC | doi




Carlomagno T, Blommers MJ, Meiler J, Cuenoud B, Griesinger C. (2001)

Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex

J. Am. Chem. Soc. 123(30):7364-7370. doi:10.1021/ja002592r
Europe PMC | doi

Hennig M, Carlomagno T, Williamson JR. (2001)

Residual dipolar coupling TOCSY for direct through space correlations of base protons and phosphorus nuclei in RNA

J. Am. Chem. Soc. 123(14):3395-3396. doi:10.1021/ja005835o
Europe PMC | doi

Carlomagno T, Prasch T, Glaser SNJ. (2001)

COIN TACSY, a novel approach to tailored correlation spectroscopy

J. Magn. Reson. 149(1):52-57.
Europe PMC

Schwalbe H, Carlomagno T, Hennig M, Junker J, Reif B, Richter C, Griesinger C. (2001)

Cross-correlated relaxation for measurement of angles between tensorial interactions

Meth. Enzymol. 338:35-81. doi:10.1016/s0076-6879(02)38215-6
Europe PMC | doi




Carlomagno T, Griesinger C. (2000)

Errors in the measurement of cross-correlated relaxation rates and how to avoid them

J. Magn. Reson. 144(2):280-287. doi:10.1006/jmre.2000.2056
Europe PMC | doi

Carlomagno T, Peti W, Griesinger C. (2000)

A new method for the simultaneous measurement of magnitude and sign of 1DCH and 1DHH dipolar couplings in methylene groups

J. Biomol. NMR 17(2):99-109. doi:10.1023/a:1008346902500
Europe PMC | doi

Carlomagno T, Maurer M, Hennig M, Griesinger C. (2000)

Ubiquitin backbone motion studied via NHN−C‘Cα dipolar−dipolar and C‘−C‘Cα/NHN CSA−dipolar cross-correlated relaxation

J. Am. Chem. Soc. 122(21):5105-5113.
Europe PMC




Carlomagno T, Felli IC, Czech M, Fischer R, Sprinzl M, Griesinger C. (1999)

Transferred cross-correlated relaxation: application to the determination of sugar pucker in an aminoacylated tRNA-mimetic weakly bound to EF-Tu

J. Am. Chem. Soc. 121(9):1945-1948.
Europe PMC




Carlomagno T, Schwalbe H, Rexroth A, Sorensen OW, Griesinger C. (1998)

New methylene specific experiments for the measurement of scalar spin-spin coupling constants between protons attached to 13C

J. Magn. Reson. 135(1):216-226. doi:10.1006/jmre.1998.1545
Europe PMC | doi




Carlomagno T, Luy B, Glaser SJ. (1997)

"Kin " HEHAHA Sequences, Heteronuclear Hartmann-Hahn Transfer with Different Bandwidths for Spins I and S

J. Magn. Reson. 126(1):110-119. doi:10.1006/jmre.1997.1157
Europe PMC | doi

Carlomagno T, Mantile G, Bazzo R, Miele L, Paolillo L, Mukherjee AB, Barbato G. (1997)

Resonance assignment and secondary structure determination and stability of the recombinant human uteroglobin with heteronuclear multidimensional NMR

J. Biomol. NMR 9(1):35-46. doi:10.1023/a:1018619501038
Europe PMC | doi




Carlomagno T, Maurer M, Sattler M, Schwendinger MG, Glaser SJ, Griesinger C. (1996)

PLUSH TACSY: Homonuclear planar TACSY with two-band selective shaped pulses applied to C(α),C' transfer and C (β),C (aromatic) correlations

J. Biomol. NMR 8(2):161-170. doi:10.1007/bf00211162
Europe PMC | doi




Benedetti E, Carlomagno T, Fraternali F, Hamada Y, Hayashi K, Paolillo L, Shioiri T. (1995)

Conformational analysis of dolastatin 10: an NMR and theoretical approach

Biopolymers 36(4):525-538. doi:10.1002/bip.360360414
Europe PMC | doi