Publikationen der Arbeitsgruppe Synthetische Chemie

2025


Ozkan, G., Oner, M. E., Fischer, A., Juadjur, A., Aganovic, K., Dräger, G., Capanoglu, E., & Esatbeyoglu, T. (2025). Effects of non-thermal food processing techniques on the composition, bioaccessibility and shelf-life of bioactive compounds in a fruit juice blend. Food Chemistry: X, 31, Artikel 103000. https://doi.org/10.1016/j.fochx.2025.103000
Luo, Y., Drexler, J., Paasche, G., Dräger, G., Zhang, H., Tang, J., Lenarz, T., & Scheper, V. (2025). 3D printing of dexamethasone-loaded polycaprolactone-enhanced alginate hydrogels for individualized implants in inner ear therapy. International Journal of Biological Macromolecules, 323, Artikel 147176. https://doi.org/10.1016/j.ijbiomac.2025.147176
Yadav, K., Kalita, T., Sharma, L., Pandit, A., Pathak, B., Dräger, G., Kirschning, A., & Chelvam, V. (2025). Design, Synthesis, and Cytotoxic Evaluation of New Structurally Simplified and Highly Potent Third-Generation Tubulysin Derivatives. Chemistry - a European journal, 31(46), Artikel e01965. https://doi.org/10.1002/chem.202501965
Jäger, B., Budde, J. L., Birke, N., Hauke, M., & Kirschning, A. (2025). Chemoenzymatic Generation of Thio-analogues of δ-Cadinene, δ-Cadinol, and a Thio-diquinane Using 8-Thio-farnesylpyrophosphate. Journal of natural products, 88(7), 1653-1662. https://doi.org/10.1021/acs.jnatprod.5c00409
Budde, J. L., Çay, M. Y., Dräger, G., Droste, J., Hassanin, A., Davari, M. D., & Kirschning, A. (2025). Reprogramming the Cyclization of the Sesquiterpene Synthase BcBOT2 Using 2,3-Z-Configured FPP Derivatives and by Means of “Methyl Mapping”. ACS catalysis, 15(10), 8125-8139. https://doi.org/10.1021/acscatal.5c01224
Ravkina, V., Dräger, G., Droste, J., Schwörer, S., Hassanin, A., Davari, M. D., & Kirschning, A. (2025). Expanding the “Terpenome”: Diterpene Synthases Accept GGPP-Ether Substrates. ACS catalysis, 15(9), 6796-6811. https://doi.org/10.1021/acscatal.5c00272
Hakim, S. E., Liu, S., Herzog, R., Arafa, A., de Vries, J., Dräger, G., & Franke, J. (2025). Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants. Journal of the American Chemical Society, 147(12), 10320-10330. https://doi.org/10.1021/jacs.4c16956
Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., & Kirschning, A. (2025). Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus. Nature Communications, 16(1), Artikel 2464. https://doi.org/10.1038/s41467-025-57013-3
Mozūraitis, R., Cirksena, K., Raftari, M., Hajkazemian, M., Mustapha Abiodun, M., Brahimi, J., Radžiutė, S., Apšegaitė, V., Bernotienė, R., Ignatowicz, L., Hick, T., Kirschning, A., Lenman, A., Gerold, G., & Emami, S. N. (2025). Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting. Communications Biology, 8(1), Artikel 139. https://doi.org/10.1038/s42003-025-07543-9
Struwe, H., Grimm, C., Dräger, G., Beutel, S., Alcalde, M., Kirschning, A., & Kara, S. (2025). Expanding the “Terpenome”: Applications of Unspecific Peroxygenases (UPOs) in Oxidations of Unnatural Terpenoids. CHEMCATCHEM, 17(1), Artikel e202401414. https://doi.org/10.1002/cctc.202401414