Publikationen der Arbeitsgruppe Naturstoffsynthese

2011


Nicolaou, K. C., Simmons, N. L., Ying, Y., Heretsch, P. M., & Chen, J. S. (2011). Enantioselective Dichlorination of Allylic Alcohols. Journal of the American Chemical Society, 133(21), 8134-8137. https://doi.org/10.1021/ja202555m
Heretsch, P., Buettner, A., Tzagkaroulaki, L., Zahn, S., Kirchner, B., & Giannis, A. (2011). Exo-Cyclopamine-a stable and potent inhibitor of hedgehog-signaling. Chemical communications, 47(26), 7362-7364. https://doi.org/10.1039/c1cc11782c

2010


Heretsch, P., Tzagkaroulaki, L., & Giannis, A. (2010). Modulators of the hedgehog signaling pathway. Bioorganic and Medicinal Chemistry, 18(18), 6613-6624. https://doi.org/10.1016/j.bmc.2010.07.038
Heretsch, P., Rabe, S., & Giannis, A. (2010). A Biomimetic Approach to C-nor-D-homo-Steroids. Journal of the American Chemical Society, 132(29), 9968-9969. https://doi.org/10.1021/ja103152k
Heretsch, P., Tzagkaroulaki, L., & Giannis, A. (2010). Cyclopamine and Hedgehog Signaling: Chemistry, Biology, Medical Perspectives. Angewandte Chemie - International Edition, 49(20), 3418-3427. https://doi.org/10.1002/anie.200906967

2009


Heretsch, P., Rabe, S., & Giannis, A. (2009). Synthesis of All Diastereomers of the Piperidine-Alkaloid Substructure of Cyclopamine. Organic letters, 11(23), 5410-5412. https://doi.org/10.1021/ol902270f
Giannis, A., Heretsch, P., Sarli, V., & Stossel, A. (2009). Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach. Angewandte Chemie - International Edition, 48(42), 7911-7914. https://doi.org/10.1002/anie.200902520

2008


Heretsch, P., Thomas, F., Aurich, A., Krautscheid, H., Sicker, D., & Giannis, A. (2008). Syntheses with a chiral building block from the citric acid cycle: (2R,3S)-Isocitric acid by fermentation of sunflower oil. Angewandte Chemie - International Edition, 47(10), 1958-1960. https://doi.org/10.1002/anie.200705000

2007


Heretsch, P., & Giannis, A. (2007). An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues. SYNTHESIS-STUTTGART, (17), 2614-2616. https://doi.org/10.1055/s-2007-983843